At BasePair , we provide custom cell culture services tailored to meet the needs of academic research, biotechnology, and pharmaceutical industries. Our expertise spans mammalian and bacterial cell culture, ensuring high-quality, reproducible results for applications such as protein expression, assay development, drug screening, and functional studies.
Why Choose Our Cell Culture Services?
- Sterile, High-Quality Cultures – Strict quality control ensures contamination-free cultures.
- Scalable & Customizable – From small-scale research projects to large-scale production.
- Dedicated BSL2 Space as necessary – BasePair has a standing Biosafety committee and experience in Biosafety Level 2 organisms including infectious, bacteria, fungi, and viral species/strains as well has BSL2 toxins including Shiga, botulinum, ricin, etc.
- Expert Cell Line Handling – We maintain, expand, and optimize diverse cell types.
- GMP & Research-Grade Options – Services available for both basic research and regulated applications.
Our Services
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Mammalian Cell Culture Services
We offer routine and custom mammalian cell culture, including primary cells and established cell lines.Cell Line Expansion & Maintenance
- Culturing of adherent and suspension cell lines.
- Routine passaging, cryopreservation, and recovery.
- Mycoplasma testing and cell authentication upon request.
Custom Cell Line Engineering
- Stable & transient transfections (plasmids, siRNA, CRISPR, viral vectors).
- Lentiviral & AAV production for gene expression studies.
- Generation of knockout/knockdown and overexpression cell lines.
Cell-Based Assay Development
- Proliferation, cytotoxicity, and viability assays.
- Reporter assays (luciferase, fluorescence, FRET).
- High-throughput screening (HTS) support.
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Bacterial Culture Services
We offer comprehensive bacterial culture solutions for plasmid preparation, recombinant protein expression, and microbiome studies.Custom Bacterial Strain Culturing
- Growth and maintenance of standard E. coli, Bacillus, Pseudomonas, and custom strains.
- Aerobic and anaerobic culture conditions available.
- Antibiotic resistance profiling and custom selective media.
Recombinant Protein Expression
- Inducible and constitutive expression systems (T7, Lac, IPTG, auto-induction).
- Protein expression in E. coli, Bacillus, yeast upon request.
- Affinity purification (His-tag, GST, FLAG, etc.) available as an add-on.
Plasmid Preparation & DNA Production
- Mini, midi, maxi, and giga-scale plasmid prep services.
- Endotoxin-free preparations for transfection-ready DNA.
- Custom cloning and vector construction services.
Applications
Our custom cell culture services support research and development in:
- Biologics & Therapeutic Development – Cell-based assays, protein production, and target validation.
- Drug Discovery & Screening – High-throughput screening, compound testing, and ADME/Tox studies.
- Synthetic Biology & Genetic Engineering – Custom microbial engineering, CRISPR-based cell models.
- Microbiome & Metabolic Research – Anaerobic bacterial culturing, metabolite analysis.
How Our Service Works
- Consultation – Discuss project needs, cell type selection, and experimental design.
- Sample Processing – We culture, expand, and modify cells per your specifications.
- Data Delivery – Cells, proteins, or plasmids are delivered along with a detailed report.
Why BasePair Bio?
- Experienced Team – Experts in cell culture, genetic engineering, and microbial biology.
- Flexible Project Design – Adaptable to custom workflows and industry standards.
- Confidential & Reliable – Secure, high-quality services with strict data protection.
- Fast Turnaround – Expedited services available upon request.
Get Started with Custom Cell Culture Services
Interested in outsourcing your cell culture needs? Contact info@basepairbio.com today to discuss your project.